Some research suggests that berberine works similarly to the drug metformin, which doctors often prescribe to treat type 2 diabetes. This tissue helps the body turn food into body heat, and increased activation may help treat obesity and metabolic syndrome. The team behind another study observed that berberine may activate brown adipose tissue. Barberry is a plant that contains high amounts of berberine.Īlso, a double-blind study found that individuals with metabolic syndrome who took 200 mg of barberry three times a day experienced decreases in their body mass index readings. One review reported that people who took 750 milligrams (mg) of barberry twice a day for 3 months had a significant decrease in weight. Obesity is a common condition that can increase the risk of: High blood pressure is a leading cause of heart disease.Ī literature review found that berberine combined with a blood-pressure-lowering drug was more effective than the drug alone.Īlso, results of a study of rats indicate that berberine could delay the onset of high blood pressure and, when it does develop, help reduce its severity. Researchers believe that the effects of berberine might be similar to those of drugs that reduce high cholesterol, while berberine does not cause the same side effects. This, in turn, helps lower total cholesterol and triglyceride levels. It may help reduce LDL, or “bad,” cholesterol and increase high-density lipoprotein, or “good,” cholesterol.Ī literature review found that berberine combined with lifestyle changes works better than lifestyle changes alone in treating high cholesterol.įurthermore, a study of hamsters observed that berberine helps move excess cholesterol to the liver, where the body can process and remove it. According to one review, studies in both animals and humans indicate that berberine has cholesterol-lowering effects. Some evidence suggests that berberine could help lower LDL cholesterol and triglyceride levels. High levels of low-density lipoprotein (LDL) cholesterol and triglycerides may increase the risk of heart disease and stroke. It may not be right for everyone and could interact with other medications. Speak with a doctor before taking berberine for diabetes. However, scientists need to conduct more large, double-blind studies to fully determine berberine’s safety and efficacy. Researchers believe this activation can help treat diabetes and related health issues, such as obesity and high cholesterol. The same analysis found that a combination of berberine and blood-sugar-lowering drugs is more effective than the drugs alone.Īccording to 2014 research, berberine shows promise as a potential diabetes treatment, especially for those who cannot take existing anti-diabetic drugs due to heart disease, liver failure, or kidney problems.Īnother literature review found that berberine combined with lifestyle changes worked better to lower blood glucose than lifestyle changes alone.īerberine appears to activate AMP-activated protein kinase, which can help regulate how the body uses blood sugar. One literature review indicated that berberine was better than a placebo at lowering blood sugar. Studies have found that it can have positive effects on: Research has shown that berberine may work as a diabetes treatment. ![]() Some 2014 research suggests that berberine has anti-inflammatory properties, which means it could help treat diabetes and other inflammation-related health conditions. Inflammation is a key factor in several health conditions, including heart disease and diabetes. aureus can cause many health problems, including:Īnother study found that berberine has the ability to damage the DNA and protein of certain bacteria. A 2016 laboratory study found that berberine helped inhibit the growth of Staphylococcus aureus. Bacterial infectionsīerberine could be an effective antimicrobial agent. The following are conditions that berberine may help treat, according to research.
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